Nanoscale Microscopy Lab Summer Institute
Participants of the Nanoscale Microscopy Lab Summer Institute will receive UCLA credit for the following course(s):
- Microbiology, Immunology, and Molecular Genetics 15 – Nanoscale Microscopy Laboratory (2 units)
MIMG 15, Nanoscale Microscopy Lab is an exploratory introduction to three key microscopy techniques for nanoscience research: fluorescence microscopy, scanning probe microscopy, and electron microscopy. Nanoscience is an umbrella term that encompasses a diverse, interdisciplinary branch of modern science research, including molecular sciences, biotechnology, material science, chemistry, biochemistry, and various fields of engineering.
Microscopy has been an indispensable tool in the advancement of nanoscience. This course aims to give an overview of the most important modalities of microscopy that are commonly used in nanoscale research. The course will begin with an introduction of the common principles of microscopy and then cover light and confocal microscopy, which itself has had a long and fascinating history. We will then move on to electron microscopy, cryo electron microscopy and tomography, and scanning probe microscopy. The course will include laboratory time for sample preparation techniques and measurements at the instruments. It will also consider few examples highlighting advanced research applications.
Students are required to make a final presentation on a team project.
PROFESSOR HONG ZHOU is a faculty at the Microbiology, Immunology & Molecular Genetics Department of UCLA. Dr. Zhou is also the Director of the Electron Imaging Center for NanoMachines. Professor Zhou's lab focuses on 3D structural studies of biological complexes using cryo-electron microscopy (cryoEM) and cryo-electron tomography (cryoET). These emerging methods are particularly suitable for structure determination of large molecular complexes, viruses, cellular machineries and bacterial cells. Recent efforts have focuses on developing and applying advanced cryoEM and cryoET techniques to visualize the dynamic processes of microbial infections and to decipher the mechanisms of fundamental biological processes. Dr. Zhou's group is at the forefront in pushing the envelope of cryoEM reconstruction to atomic resolution. Dr. Zhou was a Pew Scholar in the Biomedical Sciences, received numerous awards, including the Basil O'Connor Scholar Award, the Established Investigator Award of American Heart Association, the Burton award, and the KH Kuo Award of Distinguished Scientist.
DR. LAURENT A. BENTOLILA is a biochemist and a molecular geneticist who joined the Department of Chemistry and Biochemistry in 2002. He currently serves as the Scientific Director of both the Advanced Light Microscopy/Spectroscopy Laboratory and the Macro-Scale Imaging Laboratory at CNSI. Dr. Bentolila earned his B.S. in Biochemistry and M.S. in Genetics from Paris-XI University, Orsay and Ph.D. in Molecular Genetics and Immunology from the Pasteur Institute, Paris. He was a European Molecular Biology Organization Postdoctoral fellow at the University of California, Berkeley where he worked on the recombination and expression of antigen receptor genes in lymphocytes. Dr. Bentolila is an elected member of the CNSI Executive Committee and Education Committee. He is actively teaching in Biological Microscopy (MIMG 105) and Introduction to Molecular Imaging (M248). Since becoming Scientific Director of the Advanced Light Microscopy/Spectroscopy Laboratory at CNSI, Dr. Bentolila has developed and assembled a unique collection of custom-made and commercial light microscopy tools for the application of novel spectroscopic methods and advanced microscopy techniques used for the study of macromolecules, cellular dynamics and nano-scale characterization of biomaterials.
DR. ADAM Z. STIEG currently serves as the Scientific Director of the Nano and Pico Characterization Core Facility at CNSI as well Director of the Sci|Art NanoLab Institute. Dr. Stieg earned his B.S. with honors in Chemistry from Drew University and both his M.S. and Ph.D. in Inorganic and Physical Chemistry from UCLA. He is a member of the CNSI Executive and Education Committees. As a scientist and educator, Dr. Stieg continues to focus on the development of integrated approaches to study material systems at the interface of traditional boundaries. Through the implementation of original experimental techniques, with a specialized focus in multi-environment, high-performance scanning probe microscopes, his research seeks to bridge the gap between our current understanding of nanomaterials and their fundamental properties with how these systems tend toward complexity at increased scales of space and time. Numerous ongoing, collaborative efforts involve the study of molecular machines, nanoparticles for targeted drug delivery, inorganic carbon-based materials, directed stem cell differentiation and the pursuit of physically intelligent systems through neuromorphic computation. His research activities are augmented by active collaboration with artists and designers on various projects, installations, and public exhibitions that directly inform the scientific process and provide motivation to develop new educational content that conveys the need for creativity in innovation.
SCHEDULE AND SYLLABUS
Participants of the Nanoscale Microscopy Summer Institute will be awarded 2 units of Pass/No Pass credit after the successful completion of the program.
As a participant, you are expected to complete all assigned coursework, take all examinations, attend class regularly, and submit all required work by the end of the program. No part of the coursework may be continued beyond the close of the program unless prearranged by the student and the instructor.
The program instructor is required to assign a final grade for each student enrolled in a course. This program is offered on a P/NP grading basis. The following grades are used to report the quality of student work for this program:
|P||Passed (achievement at grade C level or better; used only for undergraduate study|
|NP||Not Passed (used only for undergraduate study)|
|NR||No grade was received from the instructor|
Courses in which students receive a P grade may count toward satisfaction of degree requirements, but these grades, as well as DR, I, and NR, are disregarded in determining a grade-point average.
TRANSFERING CREDIT UCLA is on the quarter system. While some schools are also on the quarter system, most colleges and universities are on the semester system. As a general guide to transferring quarter units to a semester system school, one semester unit or credit is worth 1.5 quarter units (e.g., 4 quarter units = 2.5 semester units).
UCLA courses are generally accepted for transfer credit, but all decisions on transferability rest with the home institution. Students should get advance approval of their UCLA Summer Sessions course selections from the home institution prior to registration.
For more information on grades, see the UCLA General Catalog.
Grades earned during the summer are recorded on an official University of California transcript. Students can view grades on MyUCLA no later than August 13.
The transcript is a permanent record that reflects all undergraduate and graduate work completed at UCLA. The transcript lists courses, units, grades, cumulative grade-point average, transfer credits, total units, and work in progress in chronological order. Note: Official transcripts are NOT automatically sent to you or your home institution.
DOCUMENT FEE Students are assessed a one-time document fee which covers fees for first-class mailing of official transcripts, diploma, and much more. Those requiring expedited or special delivery can submit a Transcript Request Form in person at the Registrar's Office. Additional charges may be assessed. Transcript Request Forms can be also picked up at 1113 Murphy Hall between 9:00 a.m. and 4:00 p.m., Monday – Friday.
VISITING UC STUDENTS Current or incoming UC students will have all UCLA summer activity appear automatically on the home UC campus transcript, and the grades earned at UCLA are included in the home UC campus grade-point average.
JUNE 24 - JUNE 29, 2018